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Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Immune thrombocytopenic purpura (ITP)

Immune thrombocytopenic purpura (ITP) is an immune disorder in which the body attacks the cells responsible for blood clotting (platelets), resulting in bleeding. The cause of ITP is not known.

People who have this disorder may have bruises or blood spots (purpura) on the skin or in the mouth. Internal bleeding is a more serious complication that can occur.

Some cases of ITP may go away on their own and do not require treatment. In other cases, treatment may be needed to prevent bleeding. Some medicines can help the body make more platelets. Steroids (such as prednisone) or other medicines may be needed to suppress the immune system. An intravenous (I.V.) infusion of a substance made from human blood plasma (immunoglobulin) may be given. Sometimes you will need to have platelet transfusions. In rare cases, the spleen may need to be removed.